IndraLab

Statements


USP28 deubiquitinates SREBF2. 2 / 2
| 2

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"USP28 deubiquitinates and stabilises SREBP2."

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"Furthermore, USP28 WT but not CA mutant decreased levels of mature SREBP2 in a pull-down assay using 6His-tagged K48-only ubiquitin (Fig. 3e), while silencing of USP28 increased the amount of SREBP2 ubiquitination detected by immunoprecipitation in A431 cells (Fig. 3f)."