IndraLab

Statements

All-trans-retinoic acid increases the amount of OTUD6B. 2 / 2
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"Indeed, ATRA treatment significantly increased OTUD6B protein level in a dose‐dependent manner and showed little effect on OTUD6A or OTUD2 expression (Figure 6A and Figure S6A, Supporting Information)."
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"Taken together, these results showed that ATRA upregulated the protein level of OTUD6B in ESCC cells and inhibited their TIC properties.Interestingly, we noted that the effects of ATRA in suppressing TIC properties were diminished in OTUD6B‐knockdown cells (Figure 6B–F)."
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