IndraLab

Statements

USP16 activates cell population proliferation. 3 / 3
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"Furthermore, in human tissues overexpression of USP16 reduces the expansion of normal fibroblasts and postnatal neural progenitors, whereas downregulation of USP16 partially rescues the proliferation defects of Down 's syndrome fibroblasts."
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"Concordantly, we found that ectopic expression of USP16 mostly restored the proliferation rate of USP16 knockdown cells."
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"Furthermore, in human tissues overexpression of USP16 reduces the expansion of normal fibroblasts and post-natal neural progenitors while downregulation of USP16 partially rescues the proliferation defects of DS fibroblasts."
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