IndraLab

Statements

USP3 binds SMARCA5 and K63. 4 / 4
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"USP3 binds SMARCA5 and removed K63-linked polyubiquitination of SMARCA5."
39500888
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"These data demonstrate that USP3 regulates cellular response to docetaxel in prostate cancer cells in a SMARCA5 dependent manner.Collectively, we reveal that USP3 binds SMARCA5 and removed K63-linked polyubiquitination of SMARCA5 to maintain its stability, which promotes DNA damage repair and chemotherapy resistance (Fig. 6K)."
39500888
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"USP3 directly binds SMARCA5 and removed K63-linked polyubiquitination of SMARCA5 to maintain its stability, which promotes DNA damage repair and chemotherapy resistance."
39500888
reach
"Mechanistically, USP3 binds SMARCA5 and removed K63-linked polyubiquitination of SMARCA5, which enhancing its stability."
39500888