IndraLab

Statements

USP44 inhibits cell population proliferation. 17 / 17
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"USP44 overexpression elevated the proliferation of CCRF-CEM cells, while USP44 knockdown suppressed the proliferation of Jurkat and MOLT-4 cells."
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"These results confirmed that USP44 knockdown enhanced the proliferation and migration of Caki-1 cells."
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"USP44 overexpression inhibits proliferation of 786-O cells and Caki-1 cells."
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"Taken together, this study demonstrates that USP44 inhibits proliferation while enhances apoptosis in CRC cells by inactivating Wnt and beta-catenin pathway via Axin1 deubiquitination."
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"Collectively, these data indicated that USP44 inhibited proliferation while promoted apoptosis in CRC by inhibiting Wnt/β-catenin pathway."
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"Depletion of USP44 inhibits proliferation, migration, and invasion in glioma cell lines."
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"USP44 overexpression inhibited the proliferation and migration of 786-O cells and Caki-1 cells significantly."
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"USP44 knockdown enhanced the proliferation and migration of 786-O cells and Caki-1 cells."
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"Collectively, these data indicated that USP44 inhibited proliferation while promoted apoptosis in CRC by inhibiting Wnt and beta-catenin pathway."
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"Taken together, these results demonstrated that USP44 inhibited proliferation of 786-O cells and Caki-1 cells."
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"USP44 overexpression reduced the BrdU-absorption capacity of 786-O cells and Caki-1 cells significantly (Fig. 2g, h), which demonstrated that USP44 can inhibit ccRCC proliferation."
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"Knockdown of USP44 inhibited proliferation, migration and invasion, induced apoptosis, and arrested cell cycle in G2/M phase in the established glioma cell lines."
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"Results showed that the ability of USP44 knockdown to promote the proliferation and migration of 786-O cells and Caki-1 cells was reduced significantly after treatment with a JNK inhibitor."
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"Here, we found that USP44 expression level was markedly decreased in CRC, and USP44 overexpression inhibited proliferation while enhanced apoptosis in CRC cells, suggesting that USP44 is a cancer suppressor in CRC."
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"Taken together, this study demonstrates that USP44 inhibits proliferation while enhances apoptosis in CRC cells by inactivating Wnt/β-catenin pathway via Axin1 deubiquitination."
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"Using 786-O cells and Caki-1 cells, we showed that USP44 overexpression inhibited proliferation of these two cell lines."
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"USP44 suppresses proliferation and enhances apoptosis in colorectal cancer cells by inactivating Wnt and beta-catenin pathway via Axin1 deubiquitination."
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