IndraLab

Statements

CYLD inhibits Tax. 4 / 4
| 4
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"CYLD inhibits Tax stimulated activation of IKK but not that of Tak1."
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"These findings suggest that CYLD negatively regulates the signaling function of Tax through inhibition of Tax ubiquitination."
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"Importantly, expression of wildtype CYLD, but not its catalytically inactive mutant, strongly inhibited Tax stimulated activation of IKK, supporting a role for Tax ubiquitination in the activation of IKK signaling."
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"CYLD inhibits Tax stimulated IKK activation via deubiquitinating Tax, although the CYLD mediated Tax deubiquitination does not affect Tax activation of Tak1."
21824392