IndraLab

Statements

BAP1 inhibits angiogenesis. 9 / 9
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"BaP1 Reduces Tumor Growth, Angiogenesis, and Tumor Proliferation."
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"Furthermore, the BaP1 treatments reduced the percentage of blood vessel (angiogenesis) around the tumor."
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"P-I metalloproteinases and L-amino acid oxidases from Bothrops species inhibit angiogenesis."
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"Furthermore, we observed that BaP1 decreased angiogenesis, characterized by a significant decrease in the vascularization formed around the tumors, as well as reduced tumor proliferation evidenced by the reduced levels of Ki67 expression in the tumors treated with the compound.Overall, our data highlights BaP1 as a molecule with a potent and selective anticancer activity against CRC cells and as a very interesting agent to disturb and counteract the important roles of lysosome in cancer."
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"In vivo results using a chicken embryo choriollantoic membrane (CAM) assay showed that BaP1 inhibits tumor growth, angiogenesis, and tumor proliferation."
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"P-I metalloproteinases and LAAO from Bothrops spp. inhibit angiogenesis ."
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"In vivo results using a chicken embryo choriollantoic membrane ( CAM ) assay showed that BaP1 inhibits tumor growth , angiogenesis , and tumor proliferation ."
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"Furthermore, our in vivo results, using CAM assay, sustained the anticancer activity of BaP1, as it was found that BaP1 inhibits tumor growth, angiogenesis and tumor proliferation, relevant hallmarks of cancer."
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"This compound reduced the survival, proliferation, and migration of human colorectal cancer cells, and BaP1 blocked in vivo tumor growth and proliferation as well as angiogenesis."
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