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PSMD14 activates cisplatin. 3 / 3
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"Then, we found that PSMD14 overexpression elevated the level of E2F1 and decreased CDDP induced apoptosis in vitro, while E2F1 silencing circumvented the resistance to CDDP mediated by PSMD14."
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"In conclusion, PSMD14 promotes bladder cancer proliferation, progression, and cisplatin resistance by regulating NCL to activate the YAP1/Hippo pathway (Fig. 9)."
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"PSMD14 increases cell resistance to cisplatin in HNSCC by enforcing E2F1/Akt/SOX2 axis mediated stemness."
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