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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

Ply activates CYLD. 3 / 3

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"CYLD was highly induced by PLY and it inhibited MKK3-p38 induced expression of PAI-1 in the lung potentiating ALI [XREF_BIBR, XREF_BIBR]."

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"CYLD was highly induced by PLY, and it inhibited MKK3-p38 kinase dependent expression of plasminogen activator inhibitor-1 (PAI-1) in lung, thereby potentiating ALI and mortality."

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"CYLD is also highly induced by pneumolysin (PLY)."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

Ply activates CYLD. 3 / 3

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