IndraLab

Statements


| 2 3

sparser
"No evidence of an epistatic interaction between these TLR4 polymorphisms and MIF polymorphisms was found."

sparser
"Additionally, no evidence for gene-gene interaction between TLR4 polymorphisms and the previously associated MIF gene polymorphisms was found (p = 0.40)."

reach
"XREF_BIBR Under lipopolysaccharide (LPS) stimulation, MIF, CD74 and toll like receptor 4 (TLR4) could form a complex that significantly stimulates cell proliferation."

reach
"In view of previously published work suggesting a role for MIF in the expression level of TLR4 XREF_BIBR, XREF_BIBR, these results suggest an association between TLR4 and MIF in patients with autoimmune disease."

sparser
"Interactions between MIF, TLR4 and TCR/CD3 are complex and understanding their nature could have translational impacts on immunomodulatory approaches for treating inflammatory and autoimmune diseases."