IndraLab

Statements


HEY1 activates USP11. 3 / 3
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"Consistent with the regulation of PML protein stability by USP11, Hey1 induced USP11 downregulation resulted in a concomitant reduction of PML protein but not mRNA."

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"These findings support the idea that Hey1 induced USP11 and PML downregulation mediates the chemoresistant effect of Notch."

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"To explore the mechanism of Hey1 induced USP11 downregulation, we analysed the 5 '-regulatory region of USP11 (XREF_FIG)."