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USP18 activates cystine. 2 / 2

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"We first confirmed that USP18 knockdown indeed reduced cystine uptake (SI Appendix, Fig. S7 H and I)."

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"We propose that during breast carcinogenesis, decreased KCTD10 and increased USP18 would cause SLC7A11 accumulation to increase cystine uptake and consumption for the maintenance of rapid metabolism."

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IndraLab

Statements

USP18 activates cystine. 2 / 2

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