IndraLab

Statements

OTUB2 decreases the amount of CA9. 2 / 2
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"Western blotting indicated that overexpression of OTUB2 and SNX29P2 reduced the protein expression levels of HIF-1α and CA9 under normoxic conditions, whereas the inactivated OTUB2 mutant did not exert such effects (Fig. 5C)."
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"As expected, overexpression of SNX29P2 inhibited the increases in the expression of HIF-1α and CA9 mediated by OTUB2 silencing under normoxic conditions, but these effects were abrogated under hypoxic conditions (Fig. 5D and SI Appendix, Fig. S5B)."
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