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USP8 activates cGAS-STING. 2 / 2
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"41 USP8, instead of USP8 C786A, enhanced the promoter activity of the IFN-β luciferase reporter induced by the plasmids expressing cGAS and STING ( Figure 5 A), suggesting that the regulation of cGAS-[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"In addition, we observed that the knockdown of USP8 in Ddx3x KO cells did not lead to a further decrease in Ifnb and Isg15 expression following HSV60 stimulation ( Figure 4 C), suggesting that the reg[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"