IndraLab

Statements

Nevirapine inhibits IFNB1. 4 / 4
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"Despite the considerable variability in the magnitude of ISG induction (Fig. S1F through I), the observed innate immune activation completely depended on reverse transcription, as the NNRTI nevirapine (NVP) prevented the induction of IFN-β and ISGs (Fig. 1D through G; Fig. S1D through I)."
38530034
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"In both cases, NVP treatment reversed the IFN-beta production."
33563288
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"As previous reported in MEF, nevirapine abrogated IFNbeta, Isg15, Il6, and Rantes induction upon HIV-VSV infection, but raltegravir had no effect."
27078069
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"AZT and NVP, even at high concentrations, did not inhibit IFNbeta induction by HT-DNA (XREF_SUPPLEMENTARY), indicating that the inhibitory effects of AZT and NVP were due to their specific inhibition of HIV reverse transcription."
23929945