IndraLab

Statements

Heparin inhibits FOS. 9 / 9
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"Because heparin is taken up by cells over a much longer time course, we addressed mechanisms whereby extracellular heparin might suppress c-fos induction at such early times."
8663360
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"Heparin suppresses mitogenic responses in renal mesangial cells, and when quiescent mesangial cells are stimulated with serum, heparin blocks the induction of c-fos seen at 15 min."
8663360
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"Inhibition of mitogenesis and c-fos induction in mesangial cells by heparin and heparan sulfates."
8821828
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"We conclude that heparin suppresses induction of c-fos in mesangial cells by blocking at least two different points in signal transduction cascades, one upstream of MAPK and the other independent of MAPK, but dependent on intracellular Ca2+."
8663360
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"We show that heparin suppressed the induction of c-fos and c-myc mRNA by serum in murine (BALB/c) 3T3 fibroblasts."
2541434
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"Heparin is a potent inhibitor of c-Fos, therefore, RPL29 may bind to heparin and induce c-Fos expression 43."
33004906
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"Previous experiments have shown that heparin inhibits induction of c-fos and c-myc protooncogene mRNA in rat VSMC stimulated by phorbol 12-myristate 13-acetate (PMA) but not when stimulated by epidermal growth factor (EGF) (Pukac, L. A., Castellot, J. J., Wright, T. C., Caleb, B. L., and Karnovsky, M. J. (1990) Cell Regul."
1371276
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"These results suggest that heparin inhibits a protein kinase C dependent pathway for cell proliferation and suppresses the induction of c-fos and c-myc mRNA at a site distal to activation of the kinase."
2541434
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"In this paper we show that heparin suppressed the induction of c-fos and c-myc mRNA in rat and calf VSMC."
2099192