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"Heparin suppresses the induction of c-fos and c-myc mRNA in murine fibroblasts by selective inhibition of a protein kinase C dependent pathway."

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"In this paper we show that heparin suppressed the induction of c-fos and c-myc mRNA in rat and calf VSMC."

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"These results suggest that heparin inhibits a protein kinase C dependent pathway for cell proliferation and suppresses the induction of c-fos and c-myc mRNA at a site distal to activation of the kinase."

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"Inhibition of mitogenesis and c-fos induction in mesangial cells by heparin and heparan sulfates."

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"Heparin suppresses mitogenic responses in renal mesangial cells, and when quiescent mesangial cells are stimulated with serum, heparin blocks the induction of c-fos seen at 15 min."

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"Because heparin is taken up by cells over a much longer time course, we addressed mechanisms whereby extracellular heparin might suppress c-fos induction at such early times."

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"Heparin suppresses the induction of c-fos and c-myc mRNA in murine fibroblasts by se- Steroids, 1995, vol."

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"Heparin suppresses the induction of c-fos and c-myc mRNA in murine fibroblasts by selective inhibition of a protein kinase C dependent pathway."

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"Previous experiments have shown that heparin inhibits induction of c-fos and c-myc protooncogene mRNA in rat VSMC stimulated by phorbol 12-myristate 13-acetate (PMA) but not when stimulated by epidermal growth factor (EGF) (Pukac, L. A., Castellot, J. J., Wright, T. C., Caleb, B. L., and Karnovsky, M. J. (1990) Cell Regul."

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"Heparin is a potent inhibitor of c-Fos, therefore, RPL29 may bind to heparin and induce c-Fos expression 43."

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"Heparin (1 microg/ml) suppressed the induction of c-fos initiated by all three treatments."

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"Heparin inhibits c-fos and c-myc mRNA ex- pression in vascular smooth muscle cells."

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"We conclude that heparin suppresses induction of c-fos in mesangial cells by blocking at least two different points in signal transduction cascades, one upstream of MAPK and the other independent of MAPK, but dependent on intracellular Ca2+."

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"Heparin selectively suppresses the induction of c- fos and c- myc mRNA in rat and calf VSMCs at the transcriptional level and inhibits VSMC growth ( Pukac et al., 1990 )."

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"Heparin inhibits Ca2 +/calmodulin-dependent kinase II activation and c-fos induction in mesangial cells."

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"We show that heparin suppressed the induction of c-fos and c-myc mRNA by serum in murine (BALB/c) 3T3 fibroblasts."

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"Heparin (1 microg/ml) suppressed ionomycin dependent c-fos induction."