IndraLab

Statements

OTUB1 inhibits MAF. 3 / 3
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eidos
"As shown in Fig. 2c , Otub1 prevented c-Maf from polyubiquitination , while Nam increased c-Maf ubiquitination and partly rescued the ubiquitination level in the presence of Otub1 ( Fig. 2c ) , suggesting that Nam antagonized Otub1 in terms of c-Maf polyubiquitination ."
32999280
reach
"Otub1 abrogates c-Maf K48 linked polyubiquitination thus preventing its degradation and enhancing its transcriptional activity."
32842143
reach
"In other words, Otub1 is essential for AVT to inhibit c-Maf activity."
33627137