IndraLab

Statements


3 | 5 3

sparser
"This analysis revealed a potential interaction between OTUB2 and TRAF6 ( xref ), and subsequent studies confirmed that TRAF6 is a substrate of OTUB2."

No evidence text available

sparser
"These results demonstrated that TRAF6 binding to OTUB2 is crucial for its induction of autophagy and selective autophagic CTNNB1 degradation."

reach
"OTUB1 and OTUB2 interact with and deubiquitinate TRAF3 and TRAF6, which are required for virus triggered IRF3 and NF-kappaB activation [XREF_BIBR]."

reach
"Coimmunoprecipitation analyses indicate that OTUB1 and OTUB2 associate with TRAF3 and TRAF6, negatively regulating antiviral responses by deubiquitinating their respective K63 linked polyubiquitin chains."

sparser
"More than this special feature, if OTUB2 interacts with TRAF6, the result should benefit the NF-kappaB pathway."

No evidence text available

reach
"This analysis revealed a potential interaction between OTUB2 and TRAF6 (Fig. 5A), and subsequent studies confirmed that TRAF6 is a substrate of OTUB2."

reach
"Therewith, we demonstrated the exogenous binding between OTUB2 and TRAF6 in HEK293T cells by Co-immunoprecipitation (Co-IP) assays (Fig. 5B)."

reach
"These results demonstrated that TRAF6 binding to OTUB2 is crucial for its induction of autophagy and selective autophagic CTNNB1 degradation."

No evidence text available