IndraLab

Statements

OTUB2 binds TRAF6. 11 / 11
3 | 5 3
biogrid
No evidence text available
23105109
sparser
"These results demonstrated that TRAF6 binding to OTUB2 is crucial for its induction of autophagy and selective autophagic CTNNB1 degradation."
36858343
reach
"This analysis revealed a potential interaction between OTUB2 and TRAF6 (Fig. 5A), and subsequent studies confirmed that TRAF6 is a substrate of OTUB2."
40296903
reach
"Therewith, we demonstrated the exogenous binding between OTUB2 and TRAF6 in HEK293T cells by Co-immunoprecipitation (Co-IP) assays (Fig. 5B)."
40296903
biogrid
No evidence text available
19996094
reach
"These results demonstrated that TRAF6 binding to OTUB2 is crucial for its induction of autophagy and selective autophagic CTNNB1 degradation."
36858343
reach
"OTUB1 and OTUB2 interact with and deubiquitinate TRAF3 and TRAF6, which are required for virus triggered IRF3 and NF-kappaB activation [XREF_BIBR]."
23151130
reach
"Coimmunoprecipitation analyses indicate that OTUB1 and OTUB2 associate with TRAF3 and TRAF6, negatively regulating antiviral responses by deubiquitinating their respective K63 linked polyubiquitin chains."
33511009
biogrid
No evidence text available
32296183
sparser
"More than this special feature, if OTUB2 interacts with TRAF6, the result should benefit the NF-kappaB pathway."
35309903
sparser
"This analysis revealed a potential interaction between OTUB2 and TRAF6 ( xref ), and subsequent studies confirmed that TRAF6 is a substrate of OTUB2."
40296903