IndraLab

Statements

BAP1 inhibits homologous recombination. 3 / 3
| 3
reach
"BAP1 is rapidly recruited to DSB sites, and BAP1 depletion leads to reduced BRCA1, RAD51 and RPA foci and has been suggested to decrease HR."
30831436
reach
"BAP1 loss specifically reduces HR but not NHEJ [68,69]."
31769469
reach
"As BAP1 loss causes deficient HR, BAP1-mutant tumors were reported to be particularly addicted to alternative DNA repair pathways, e.g., PARP1 mediated ones."
33072611