
IndraLab
Statements
USP37 inhibits homologous recombination. 2 / 2
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2
✎
reach
"We reasoned that USP26 and USP37 may antagonize the RAP80 dependent sequestration of BRCA1 by removing RNF8 and RNF168 mediated ubiquitylation and thereby promote HR."
✎
reach
"Depletion of USP26 or USP37 disrupts the execution of HR and this effect is alleviated by the simultaneous depletion of RAP80."