IndraLab

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TWIST1 decreases the amount of USP13. 3 / 3
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"Twist1 inhibits USP13 promoter transcription."
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"Drawn from the combined results from the ChIP and luciferase reporter assays, we found that Twist1 can inhibit the transcription of USP13 by directly binding to these three E-box regions."
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"Twist1 overexpression decreased USP13 mRNA levels in T47D and ZR-75–30 cells, whereas Twist1 knockdown increased USP13 mRNA levels in SUM159PT and MDA-MB231 cells (Fig. 7e)."
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