IndraLab

Statements


SMAD4 bound to SP1 activates SMAD4. 1 / 1
1 |

"Smads 3 and 4 have specifically been shown to take part in TGF-beta-mediated CTCF/Smads complex binding of the APP gene promoter that up-regulates APP expression In addition, TGF-beta has been shown to stimulate Smads interaction with the stimulating protein 1 (SP1) transcription factor"