IndraLab

Statements


USP2 deubiquitinates TWIST1. 2 / 2
| 2

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"Furthermore, TJP1 recruited USP2, which deubiquitinated TWIST1, thereby protecting TWIST1 from proteasome-mediated protein degradation."

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"USP2 regulates Bmi1 and EMT by Twist stabilization and prevents Twist ubiquitination driven by beta-TrCP and subsequent proteasome mediated protein degradation."