IndraLab

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OTUB1 activates CD8. 2 / 2

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reach

"Otub1 deficiency greatly enhances antigen specific CD8 T cell responses and promotes their metabolic reprogramming and effector function in antitumor immunity."

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reach

"Otub1 deficiency in mice causes aberrant responses of CD8 + T cells to IL-15, rendering naive CD8 + T cells hypersensitive to antigen stimulation characterized by enhanced metabolic reprograming and effector functions."

31182807

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

OTUB1 activates CD8. 2 / 2

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