IndraLab

Statements

Beta2 subunit inhibits KCNMA1. 3 / 3
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"To determine whether beta2 subunit can promote targeting of hSlo to an endosomal compartment, cells were co-transfected with both hSlo and beta2 subunits, together with RhoB."
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"It is well established that, in addition to its gating shifts, the beta2 subunit slows BK channel activation."
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"The amino-terminal residues 2-4 of the beta2 subunit may directly block the BK channel to cause inactivation, and the amino-terminal 33 residues of the beta3 subunit also play a critical role in causing BK inactivation."
15897294