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BAP1 activates RAD51. 2 / 2

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"BAP1 depletion abrogates the binding of INO80 to replication forks and increases the formation of RAD51 foci following HU treatment."

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"BAP1 can deubiquitylate Ub-H2AK119 at the site of UV-induced DNA damage, and promote DNA repair by regulating the accumulation of repair proteins (BRCA1, RAD51, and RPA) (7)."

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INDRA sources:

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IndraLab

Statements

BAP1 activates RAD51. 2 / 2

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