IndraLab

Statements

USP4 increases the amount of USP4. 4 / 4
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"The results of IHC staining demonstrated that USP4 expression in xenograft tumors was decreased by USP4 downregulation but increased by USP4 overexpression (Supplementary Fig. 1E)."
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"Specific inhibitory siRNA of USP4 reduced USP4 level and the parameters mentioned above."
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"By inhibiting the expression of USP4, down-regulation of USP4 inhibited the proliferation, migration, and apoptosis of hypertrophic scar fibroblasts through the TGF-beta and Smad7 signaling pathway."
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"Reduced USP4 expression by si-USP4, verified by immunoblotting (Fig. 3C), led to a clear downregulation in KLF2 protein level in MM1.S/BTZ and NCI-H929/BTZ cells (Fig. 3D)."
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