IndraLab

Statements


USP46 inhibits Wingless. 2 / 2
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"Together, these findings provide additional evidence that Usp46 promotes Wingless signaling in the larval wing disc.Inactivation of Wdr20 and Uaf1 using the same approach also decreased Wingless signaling in the wing disc."

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"These findings reveal that in a manner similar to known Wingless pathway components, the Usp46 complex non-autonomously restricts proliferation of neighboring ISCs, providing additional evidence that Usp46 promotes Wingless signaling during intestinal homeostasis."