IndraLab

Statements

USP9X activates epithelial to mesenchymal transition. 4 / 4
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reach
"Knockdown of USP9X in pancreatic cells reduced cell growth, migration, and invasion, downregulated EMT markers, and increased apoptosis in vitro and in vivo [158,159,160]."
35884607
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"Thus, USP9X may mediate the function of TGF-β1 on promoting CSCs occurrence and EMT transition in vitro.In vivo, orthotopic tumor models were established via injecting the luciferase-expressing ID8 cells (ID8-luc) into the ovarian bursal cavity of C57BL/6 mice and visualized with Caliper IVIS Spectrum System."
40246814
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"In addition, miR-132 was previously shown to target USP9X-induced EMT, which led to inhibition of the migration and invasive capabilities of NSCLC cells (97)."
37920433
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"Our analysis of clinical HCC samples verifies that miR-26b also targets USP9X expression to inhibit the EMT of hepatocytes."
24890815