IndraLab

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CYLD-C601A activates NFkappaB. 1 / 1
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"Also, activation of NF-kappaB by ectopic XIAP, an essential Ub ligase for NOD2 signaling, was blocked by overexpression of CYLD WT, but not CYLD C601A, which increased NF-kappaB activity (XREF_FIG D and XREF_SUPPLEMENTARY C)."