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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

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COPS5 activates SOX9. 4 / 4

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"Moreover, in Jab1 knockout mutants, Sox9 expression and activity was severely compromised, suggesting Jab1 positively regulates Sox9 in early growth plate development."

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"Notably, Jab1 by itself did not activate Sox9 reporter in 10T1/2 cells (XREF_FIG)."

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"Jab1 likely promotes Sox9 and BMP signaling activity during early limb development."

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"Additionally, Jab1 can increase Sox9 transcriptional activity in 10T1/2 cells (XREF_FIG)."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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COPS5 activates SOX9. 4 / 4

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