IndraLab

Statements

EC 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitor inhibits STAT1. 2 / 2
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"Immunogenic ferroptosis induced by BEBT-908 (PI3K inhibitor) leads to upregulation of major histocompatibility complex I (MHC-I) and activation of endogenous IFN-γ via STAT1, thereby activating the antitumor immune response and enhancing anti-PD1 therapy, effectively inhibits tumor growth [171]."
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"To investigate this possibility, we determined the effect of FLUD (a specific STAT1 inhibitor), PD98059 (a specific MEK inhibitor), SB202190 (a specific p38 MAPK inhibitor), and LY294002 (a specific PI3K inhibitor) on gp120 induced STAT1 activation."
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