IndraLab

Statements

USP15 binds XDH. 3 / 3
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reach
"Mechanistically, XOR physically interacts with USP15, thereby promoting deubiquitination of Kelch Like ECH Associated Protein 1 (KEAP1) to stabilize its expression, which leads to degradation of Nrf2 via ubiquitination and subsequently reactive oxygen species (ROS) accumulation in liver CSCs."
31578733
sparser
"Mechanistically, XOR physically interacts with USP15, thereby promoting deubiquitination of Kelch Like ECH Associated Protein 1 (KEAP1) to stabilize its expression, which leads to degradation of Nrf2 via ubiquitination and subsequently reactive oxygen species (ROS) accumulation in liver CSCs."
31578733
sparser
"USP15 physically interacts with XOR and stabilizes Kelch-like ECH, which is attributed to ROS accumulation in hepatocellular carcinoma [ xref ]."
36163170