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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

KCNQ4-G285S inhibits potassium(1+). 1 / 1

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"Kubisch and colleagues have shown that the G285S mutation of KCNQ4 lies in the conserved channel pore region in exon 6 and abolishes ~ 90% of the potassium current of wild type KCNQ4 in the Xenopus oocyte system, reflecting a strong dominant negative effect."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...