IndraLab

Statements

LMP1 activates UCHL1. 4 / 4
| 4
reach
"Therefore, SP1, STAT3, and c-JUN are likely candidates to contribute to LANA- and LMP1 induced activation of the uch-l1 promoter and will be the subject of future studies."
24314660
reach
"Finally, the mechanism by which LANA and LMP1 induce the uch-l1 promoter was explored."
24314660
reach
"In addition, we demonstrate that EBV LMP1 can also activate the uch-l1 promoter and increase levels of UCH-L1."
24314660
reach
"The finding that KSHV LANA can itself induce the expression of EBV LMP1 suggests there is a second mechanism through which UCH-L1 levels are augmented in co-infected cells : LANA activates the expression of LMP1, which in turn activates the uch-l1 promoter, resulting in greater levels of UCH-L1."
24314660