IndraLab

Statements

CACNA1B binds syntaxin. 5 / 5
| 5
sparser
"Our findings are in agreement with earlier studies which reported that interruption of the CaV2.2–syntaxin interaction with synprint peptides inhibits fast, synchronous transmitter release. xref "
28767512
sparser
"If syntaxin interaction with Cav2.2 primarily serves to localize the channel to the exocytotic machinery [ xref ], rather than modulating channel activity, this may reconcile the findings that PKC does not affect calcium channel currents but that channel modification by PKC is an important regulatory mechanism."
29029784
sparser
"If syntaxin interaction with Cav2.2 primarily serves to localize the channel to the exocytotic machinery [101] , rather than modulating channel activity, this may reconcile the findings that PKC does[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
29029784
sparser
"The notion of PPIs altering CaV2.2 channel function was proposed almost two decades ago by William Catterall and colleagues who discovered that interruption of the CaV2.2-syntaxin interaction with SYNaptic Protein INTeraction (synprint) peptides inhibits fast, synchronous transmitter release [ xref , xref , xref , xref ]."
23831344
sparser
"PKC increases the interaction of syntaxin with Cav2.2 which modulates the calcium channel whereas phosphorylated synaptotagmin increases the affinity of insulin granules to SNARE complex near the memb[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
29422234