IndraLab

Statements

(-)-epigallocatechin 3-gallate inhibits TRAF6. 5 / 8
| 5
reach
"EGCG inhibited the activation of NF-kappaB and the upregulation of TLR 2, 4 and 9 as well as their adaptors MyD88 and TRAF6 in the lungs following PQ challenge."
27890776
reach
"3) EGCG (20mg/Kg, i.p.), 1, 24 and 48h after paraquat administration in mice, attenuates ALI, the activation of NF-kappaB and upregulation of toll like receptor 2, 4 and 9, as well as their adaptors MyD88 and TRAF6 in the lung."
34054222
reach
"Next, our results demonstrated that EGCG suppresses the E3 ubiquitin ligase activity of TRAF6 in vitro and in vivo."
27791197
reach
"EGCG impairs the E3 ubiquitin ligase activity of TRAF6."
27791197
reach
"We observed that EGCG decreased the triglyceride (TG) concentration in rat livers and suppressed TLR4, TRAF6, IKKbeta, p-IKKbeta, p-NF-kappaB, and TNF-alpha levels compared with those in the HFD group, whereas PI3K, AKT, IRS-1, and IRS-2 indicators were improved."
32281563