IndraLab

Statements

ZUP1 activates Ubiquitin. 2 / 2
| 2
reach
"In line with the UBZ/MIU-mediated selective binding of ZUFSP to K63-linked Ub chains and the key role of this modification in promoting protein recruitment to DNA damage sites ( Jackson and Durocher, [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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reach
"POH1 and USP5 possibly acting in concert is one example, while the K63-specific activity of ZUP1 may potentially allow Ub chain editing by neighbouring E3 ligases and/or regulated extraction of target proteins from chromatin via VCP/p97."
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