IndraLab

Statements


BRCC3 inhibits RNF168. 2 / 2
| 2

reach
"In this complex, BRCC36 works together with the proteins NBA1, ABRO1, ABRA1 and BRCC45 in cleaving K63 linked ubiquitin chains and therefore seems to antagonize the ubiquitinating function of UBC13, RNF8 and RNF168."

reach
"BRCC36 and POH1 antagonize the actions of RNF8 and RNF168, hydrolyzing the K63 linkages that promote 53BP1 recruitment."