IndraLab

Statements


USP1 inhibits BRCA1. 3 / 3
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"Given that USP1 suppresses BRCA1, we expect that compromising APC function would also lead to an apparent suppression on BRCA1 focus formation."

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"Because TS requires BRCA1 (50), USP1 inhibition may lead to inconclusive repair in BRCA1 mutant cells."

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"However, although USP1 inactivation using the selective inhibitor ML323 ( Liang et al., 2014 ) produces a synthetic lethal phenotype in BRCA1-deficient cells, experimental evidence supported that a la[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"