IndraLab

Statements

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal inhibits MAVS. 5 / 6
| 5
reach
"To address whether proteasomal or lysosomal degradation is involved in US9 mediated MAVS reduction, HEK293T cells were treated with either MG132, a proteasome inhibitor, or chloroquine, a lysosome inhibitor."
29317664
reach
"In the meantime, the treatment of MG132, a proteasome inhibitor, rescued CORT caused decrease of MAVS in virus exposed A549 cells."
32943610
reach
"Treatment with a proteasome inhibitor MG132 effectively blocked MAVS degradation."
34696420
reach
"Addition of the proteasome inhibitor MG132 potently inhibited the cleavage of MAVS relative to cells treated with apoptosis-inducers alone (XREF_FIG)."
18692023
reach
"Finally, in agreement with confocal data, addition of MG132 to STS incubated cells reverses the change in MAVS localization, the majority being found in the membrane fraction as expected (XREF_FIG)."
18692023