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Tanespimycin inhibits RIPK1. 2 / 2

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"In both H23 and HepG2 cells, the Hsp90 inhibitor 17AAG caused dramatic degradation of RIP1 and IKKbeta, two critical components for TNF-alpha-induced NF-kappaB activation, regardless of the presence of SMC3."

20862547

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"A reduction in the cellular levels of RIP1 was also observed in those cell lines treated with 17AAG."

19632771

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Tanespimycin inhibits RIPK1. 2 / 2

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