IndraLab

Statements

OTUB1 binds ATF6. 5 / 5
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"We found that OTUB1 binds and stabilizes ATF6 by deubiquitination, thereby promoting the ATF6 signaling cascade."
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"We performed coimmunoprecipitation experiments to explore the possibility that OTUB1 and ATF6 directly interact."
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"As shown in Figure xref , endogenous interactions between OTUB1 and ATF6 were confirmed in T24 cells."
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"Taken together, these results show that OTUB1 interacts with ATF6 and regulates its stability by inhibiting ubiquitination."
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"OTUB1 interacts with ATF6 and enhances its stability by inhibiting ubiquitination, thereby promoting the migration and proliferation of bladder cancer cells ( xref )."
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