IndraLab

Statements

Hydroxychloroquine inhibits dioxygen. 4 / 4
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"In murine models of SLE, hydroxychloroquine decreased reactive oxygen species production via NADPH, improving nitric oxide availability and preventing endothelial dysfunction."
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"Vascular reactive oxygen species content and mRNA levels of nicotinamide adenine dinucleotide phosphate oxidase subunits NOX-1 and p47 (phox) were increased in lupus mice and reduced by hydroxychloroquine or antioxidants."
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"Besides, in metastatic kidney cancer cells, HCQ inhibited cell growth, oxygen consumption and mitochondrial respiration [59]."
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"HCQ treatment inhibits cell growth and mitochondrial oxygen consumption, promotes apoptosis of RCC tumor cells and increases glycolysis rates in RCC cells [25]."
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