IndraLab

Statements

Plumbagin inhibits RELA. 4 / 4
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"In addition, NF-kappaB and p65 activation in RAW 264.7 cells was decreased by plumbagin (XREF_SUPPLEMENTARY)."
27756878
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"Interestingly, plumbagin also increases EGF, VEGF and FGF, decreases MMP-2, COX-2, iNOS, CD8, CD163, as well as NF-κB p65, and suppresses IL-6 and IL-1β (101)."
36875064
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"Also, plumbagin increased EGF, VEGF and FGF, decreased MMP-2, COX-2, iNOS, CD8, CD163 and NF-kB p65 and suppressed IL-6 and IL-1β [33]."
37998956
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"Plumbagin also suppressed the direct binding of nuclear p65 and recombinant p65 to the DNA, and this binding was reversed by dithiothreitol both in vitro and in vivo."
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