IndraLab

Statements


TP53 binds USP7 and EBNA1. 3 / 3
| 3

sparser
"Crystal structure analysis showed that USP7 binds to its substrate p53 and its inhibitory interactor Epstein–Barr nuclear antigen 1 (EBNA1) protein through the same pocket but the former binding partner p53 exhibit weaker contacts with USP7 [ xref , xref ]."

sparser
"NMR studies of USP7 bound by EBNA1 and p53 indicated that p53 and EBNA bind the same pocket but p53 but makes less extensive contacts with USP7."

sparser
"The results of these experiments demonstrated that the deletion of Ubl2 did not inhibit the interaction of USP7 with p53 or EBNA1 ( xref , A and B )."