IndraLab

Statements

USP2 inhibits inflammatory response. 4 / 4
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"Moreover, macrophage USP2 represses adipose tissue inflammation and subsequent insulin resistance [79]."
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"Macrophage USP2 may therefore selectively prevent age- and/or adiposity related chronic inflammation and subsequent insulin resistance."
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"Substrates of USP2 remaining unidentified, its presence in adipose tissue macrophages inhibits chronic inflammation in adipose tissue [20]."
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"Overexpression of USP2 via tail injection of recombinant adeno-associated virus serotype 9 (AAV9) in TAC-treated male mice has been reported to attenuate pressure-overload-induced ventricular dysfunction, cardiac fibrosis, inflammation, and overall oxidative stress compared with AAV9 control-treated counterparts [31]."
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