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USP44 deubiquitinates AXIN1. 2 / 3

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"This indicates that USP44 deubiquitination of Axin1 increases beta-catenin degradation, inhibits Wnt and beta-catenin signaling, and affects CRC [XREF_BIBR]."

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"USP44, for instance, reduces AXIN1 ubiquitination to inhibit colorectal cancer cell proliferation [70]."

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USP44 deubiquitinates AXIN1. 2 / 3

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