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PKM2 inhibits USP35. 3 / 3
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"EdU assays demonstrated that PKM2 overexpression significantly abolished the inhibitory effects of USP35 knockdown on proliferation (Fig. 7C and D)."
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"Moreover, increased PKM2 expression significantly decreased the inhibitory effect of USP35 knockdown on migration and invasion in Huh-7-De-USP35 and Hep3B-De-USP35 cells (Fig. 7E-H)."
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"It was found that increased PKM2 expression significantly abolished the inhibitory effects of USP35 knockdown on glucose uptake in Huh-7-De-USP35 and Hep3B-De-USP35 cells (Fig. 8A and E)."
37594129