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USP28 deubiquitinates ub-K119-H2A. 1 / 1
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"Elevated ub-K119-H2A has the capacity to reduce p53, p21 and p16 , indicating that USP28, which can deubiquitinate and lead to a decrease in ub-K119-H2A, has the ability to enhance the suppression of carcinogenesis by mediating p53, p21 and p16 [32]."